Voltin, Conrad-Amadeus and Mettler, Jasmin and Grosse, Jirka and Dietlein, Markus and Baues, Christian and Schmitz, Christine and Borchmann, Peter and Kobe, Carsten and Hellwig, Dirk (2020) FDG-PET Imaging for Hodgkin and Diffuse Large B-Cell Lymphoma-An Updated Overview. CANCERS, 12 (3): 601. ISSN 2072-6694
Full text not available from this repository. (Request a copy)Abstract
Since the mid-1990s, F-18-fluorodeoxglucose (FDG)-positron emission tomography (PET) in combination with computed tomography has come to play a prominent role in the management of malignant lymphomas. One of the first PET applications in oncology was the detection of lymphoma manifestations at staging, where it has shown high sensitivity. Nowadays, this imaging modality is also used during treatment to evaluate the individual chemosensitivity and adapt further therapy accordingly. If the end-of-treatment PET is negative, irradiation in advanced-stage Hodgkin lymphoma patients can be safely omitted after highly effective chemotherapy. Thus far, lymphoma response assessment has mainly been performed using visual criteria, such as the Deauville five-point scale, which became the international standard in 2014. However, novel measures such as metabolic tumor volume or total lesion glycolysis have recently been recognized by several working groups and may further increase the diagnostic and prognostic value of FDG-PET in the future.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | POSITRON-EMISSION-TOMOGRAPHY; BONE-MARROW INVOLVEMENT; METABOLIC TUMOR VOLUME; PROGNOSTIC VALUE; FOLLOW-UP; RESPONSE EVALUATION; ADAPTED TREATMENT; 1ST-LINE THERAPY; ELDERLY-PATIENTS; PREDICTIVE-VALUE; Hodgkin lymphoma; diffuse large B-cell lymphoma; positron emission tomography; staging; response assessment |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Nuklearmedizin |
| Depositing User: | Petra Gürster |
| Date Deposited: | 09 Apr 2021 06:06 |
| Last Modified: | 09 Apr 2021 06:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/44980 |
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