Mohty, Mohamad and Malard, Florent and Abecasis, Manuel and Aerts, Erik and Alaskar, Ahmed S. and Aljurf, Mahmoud and Arat, Mutlu and Bader, Peter and Baron, Frederic and Basak, Grzegorz and Bazarbachi, Ali and Blaise, Didier and Ciceri, Fabio and Corbacioglu, Selim and Dalle, Jean-Hugues and Dignan, Fiona and Fukuda, Takahiro and Huynh, Anne and Kuball, Jurgen and Lachance, Silvy and Lazarus, Hillard and Masszi, Tamas and Michallet, Mauricette and Nagler, Arnon and NiChonghaile, Mairead and Okamoto, Shinichiro and Pagliuca, Antonio and Peters, Christina and Petersen, Finn B. and Richardson, Paul G. and Ruutu, Tapani and Saber, Wael and Savani, Bipin N. and Soiffer, Robert and Styczynski, Jan and Wallhult, Elisabeth and Yakoub-Agha, Ibrahim and Duarte, Rafael F. and Carreras, Enric (2020) Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group. BONE MARROW TRANSPLANTATION, 55 (3). pp. 485-495. ISSN 0268-3369, 1476-5365
Full text not available from this repository. (Request a copy)Abstract
Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). While SOS/VOD may resolve within a few weeks in the majority of patients with mild-to-moderate disease, the most severe forms result in multiorgan dysfunction and are associated with a high mortality rate (>80%). Therefore, careful surveillance may allow early detection of SOS/VOD, particularly as the licensed available drug is proven to be effective and reduce mortality. The aim of this work is to propose an international consensus guideline for the treatment and prevention of SOS/VOD in adult patients, on behalf of an international expert group.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEPATIC VENOOCCLUSIVE DISEASE; STEM-CELL TRANSPLANTATION; BONE-MARROW-TRANSPLANTATION; HAPLOIDENTICAL DONOR TRANSPLANTATION; REGIMEN-RELATED TOXICITIES; URSODEOXYCHOLIC ACID; PERIPHERAL-BLOOD; EUROPEAN-SOCIETY; RANDOMIZED-TRIAL; PD-1 BLOCKADE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Mar 2021 11:41 |
| Last Modified: | 29 Mar 2021 11:41 |
| URI: | https://pred.uni-regensburg.de/id/eprint/45018 |
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