Antibiotic stewardship (ABS). Part 2: Application

Wendt, S. and Ranft, D. and de With, K. and Kern, W. V. and Salzberger, B. and Luebbert, Christoph (2020) Antibiotic stewardship (ABS). Part 2: Application. INTERNIST, 61 (5). pp. 475-486. ISSN 0020-9554, 1432-1289

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Abstract

Antibiotic stewardship (ABS) is an important measure to counteract the spread of resistant pathogens and multidrug resistance. The most important ABS tools include the implementation of local guidelines, the development of a house-related list of anti-infective agents, regular ABS visits and practice-oriented internal training events. Effective strategies for therapy optimization include indication testing and therapy evaluation, dose optimization as well as determining an appropriate duration of therapy. Oralization of anti-infectives (sequence therapy) should be supported by consistent clinical criteria in in-house guidelines. The incidence of Clostridioides difficile infections (CDI) can be more than halved by restricting the so-called "4C antibiotics". Point-of-care tests help to minimize the use of antibiotics in the outpatient setting. Vaccination reduces the need for antibiotic therapy.

Item Type: Article
Uncontrolled Keywords: CLOSTRIDIUM-DIFFICILE INFECTION; INTERVENTIONS; Antimicrobial stewardship; Anti-bacterial agents; Guidelines; local; Clostridioides difficile; Vaccination
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin I
Depositing User: Dr. Gernot Deinzer
Date Deposited: 30 Mar 2021 09:10
Last Modified: 30 Mar 2021 09:10
URI: https://pred.uni-regensburg.de/id/eprint/45064

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