Michalik, Katharina and Beyer, Lukas and Zeman, Florian and Wendl, Christina and Rennert, Janine and Fellner, Claudia and Stroszczynski, Christian and Wiggermann, Philipp (2020) Signal intensity in the dentate nucleus after cumulative dose of Gd-EOB-DTPA: First results of a prospective longitudinal study. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 76 (2). pp. 233-240. ISSN 1386-0291, 1875-8622
Full text not available from this repository. (Request a copy)Abstract
Gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) is a hepatocyte-specific, linear ionic contrast agent for MRI. In comparison to other linear contrast agents Gd-EOB-DTPA is excreted equally through liver and kidneys. This prospective longitudinal study investigates the signal intensity (SI) in the dentate nucleus (DN) on unenhanced T1-weighted images after repetitive application of Gd-EOB-DTPA. 46 patients were included into the study and 107 MRI examinations were performed. Statistical analysis of 25 patients showed no significant correlation between cumulative dose of Gd-EOB-DTPA and SI change and between the DN/Pons ratio(last) and the mean DN/Pons ratio(first). Subgroup analysis however revealed a significant correlation for one out of two readers. Gd-EOB-DTPA deposition could not be proven in the framework of this study.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | UNENHANCED T1-WEIGHTED IMAGES; GLOBUS-PALLIDUS; CONTRAST AGENTS; MR-IMAGES; HEPATIC-UPTAKE; GADOLINIUM; ADMINISTRATIONS; DIMEGLUMINE; GADODIAMIDE; GADOXETATE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Apr 2021 09:01 |
| Last Modified: | 06 Apr 2021 09:01 |
| URI: | https://pred.uni-regensburg.de/id/eprint/45403 |
Actions (login required)
 |
View Item |
