Contrast-enhanced ultrasound (CEUS) of cystic renal lesions in comparison to CT and MRI in a multicenter setting

Lerchbaumer, Markus Herbert and Putz, Franz Josef and Ruebenthaler, Johannes and Rogasch, Julian and Jung, Ernst-Michael and Clevert, Dirk-Andre and Hamm, Bernd and Makowski, Marcus and Fischer, Thomas (2020) Contrast-enhanced ultrasound (CEUS) of cystic renal lesions in comparison to CT and MRI in a multicenter setting. CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 75 (4). pp. 419-429. ISSN 1386-0291, 1875-8622

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Abstract

PURPOSE: Contrast-enhanced-ultrasound (CEUS) has been frequently used in assessment of cystic renal lesions. OBJECTIVE: The aim of this study was to investigate the Bosniak classification in CEUS compared to CT and MRI in a multi-center setting. METHODS: Bosniak classification in CEUS examinations of cystic renal lesions were compared to imaging findings in computed-tomography (ceCT) and magnetic-resonance-imaging (ceMRI). Imaging results were correlated to histopathological reports. All examinations were performed by experts (EFSUMB level 3) using up-to-date CEUS examination-protocols. RESULTS: Overall, 173 cystic renal lesions were compared to subgroups CT (n = 87) and MRI (n = 86). Using Bosniak-classification 64/87 renal cysts (73.6%) were rated equal compared to CT with upgrade of four lesions (4.6%) and downgrade of 19 lesions (21.8%) by CT (Intra-class-correlation [ICC] coefficient of 0.824 [p <0.001]). CEUS compared to MRI, presenting different scoring especially in classes Bosniak IIF (n = 16/31) and Bosniak III (n = 16/28) with an ICC coefficient of 0.651 (p <0.001). CONCLUSION: CEUS can visualize even finest septal and small nodular wall enhancement, which may result in an upgrade of cystic lesions into a higher Bosniak class compared to CT or MRI. Thus, a modification of the Bosniak classification on CEUS may reduce unnecessary biopsies and surgery.

Item Type: Article
Uncontrolled Keywords: BOSNIAK CLASSIFICATION; COMPUTED-TOMOGRAPHY; MASSES; PREVALENCE; UPDATE; SYSTEM; US; Contrast-enhanced ultrasound; CEUS; Bosniak; renal cyst
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Abteilung für Nephrologie
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Apr 2021 10:58
Last Modified: 06 Apr 2021 10:58
URI: https://pred.uni-regensburg.de/id/eprint/45426

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