Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension

Richter, Manuel J. and Harutyunova, Satenik and Bollmann, Tom and Classen, Simon and Fuge, Jan and Gall, Henning and Gerhardt, Felix and Ghofrani, Hossein A. and Gunkel, Hartmut and Gruenig, Ekkehard and Halank, Michael and Heine, Alexander and Klose, Hans and Lange, Tobias J. and Neurohr, Claus and Nickolaus, Kai and Opitz, Christian F. and Rosenkranz, Stephan and Seyfarth, Hans-Juergen and Tello, Khodr and Ewert, Ralf and Olsson, Karen M. (2020) Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension. PULMONARY CIRCULATION, 10 (1): 2045894020. ISSN 2045-8932, 2045-8940

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Abstract

Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro (R) pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.

Item Type: Article
Uncontrolled Keywords: SYSTEM; SAFETY; implantable infusion pump; pulmonary hypertension; treatment; prostanoid
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Apr 2021 08:32
Last Modified: 07 Apr 2021 08:32
URI: https://pred.uni-regensburg.de/id/eprint/45487

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