Dollinger, Marco and Beyer, Lukas Philipp and Haimerl, Michael and Niessen, Christoph and Jung, Ernst-Michael and Zeman, Florian and Stroszczynski, Christian and Wiggermann, Philipp (2015) Adverse effects of irreversible electroporation of malignant liver tumors under CT fluoroscopic guidance: a single-center experience. DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY, 21 (6). pp. 471-475. ISSN 1305-3825, 1305-3612
Full text not available from this repository. (Request a copy)Abstract
PURPOSE We aimed to describe the frequency of adverse events after computed tomography (CT) fluoroscopy- guided irreversible electroporation (IRE) of malignant hepatic tumors and their risk factors. METHODS We retrospectively analyzed 85 IRE ablation procedures of 114 malignant liver tumors (52 primary and 62 secondary) not suitable for resection or thermal ablation in 56 patients (42 men and 14 women; median age, 61 years) with regard to mortality and treatment-related complications. Complications were evaluated according to the standardized grading system of the Society of Interventional Radiology. Factors influencing the occurrence of major and minor complications were investigated. RESULTS No IRE-related death occurred. Major complications occurred in 7.1% of IRE procedures (6/85), while minor complications occurred in 18.8% (16/85). The most frequent major complication was postablative abscess (4.7%, 4/85) which affected patients with bilioenteric anastomosis significantly more often than patients without this condition (43% vs. 1.3%, P = 0.010). Bilioenteric anastomosis was additionally identified as a risk factor for major complications in general (P = 0.002). Minor complications mainly consisted of hemorrhage and portal vein branch thrombosis. CONCLUSION The current study suggests that CT fluoroscopy-guided IRE ablation of malignant liver tumors may be a relatively low-risk procedure. However, patients with bilioenteric anastomosis seem to have an increased risk of postablative abscess formation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PERCUTANEOUS RADIOFREQUENCY ABLATION; HEPATIC-TUMORS; HEPATOCELLULAR-CARCINOMA; ABSCESS FORMATION; TISSUE ABLATION; RISK-FACTORS; BLOOD-FLOW; COMPLICATIONS; CHEMOEMBOLIZATION; COAGULATION; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 May 2019 11:16 |
| Last Modified: | 09 May 2019 11:16 |
| URI: | https://pred.uni-regensburg.de/id/eprint/4572 |
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