Kieninger, Martin and Mandlinger, Andreas and Doblinger, Nina and Kieninger, Barbel and Bele, Sylvia and Salzberger, Bernd and Schneider-Brachert, Wulf and Graf, Bernhard and Zeman, Florian and Holzmann, Thomas (2021) Impact of the implementation of a standard for preanalytical handling of samples for microbiological diagnostics on the quality of results at a neurocritical care unit. MEDICINE, 100 (34): e27060. ISSN 0025-7974, 1536-5964
Full text not available from this repository. (Request a copy)Abstract
Antibiotic stewardship (ABS) programs intend to improve outcomes of nosocomial infections and to counteract the emergence of further antimicrobial resistances. At the anesthesiologic-neurosurgical intensive care unit (ICU) of the University Medical Center Regensburg (Germany) we implemented a standard operating procedure (SOP) with clear instructions for the preanalytical handling and storage of microbiological samples. We intended to find out whether the instructions given in the SOP led to a higher rate of ideal material being sent to the laboratory and to overall better quality of the received results. We retraced retrospectively all samples taken in cases of suspected pneumonia, urinary tract infection, bloodstream infection, catheter infection associated with a central venous or arterial catheter and ventriculitis due to external ventricular drainage as well as all smears taken for the screening for multi-resistant bacteria within a time period of 1 year before to 1 year after the implementation of the SOP. In the case of suspected pneumonia and urinary tract infection, large amounts of ideal material were sent to the microbiological laboratory. A remarkable improvement after the implementation of the SOP, however, could only be observed regarding the number of urine samples taken from older urinary catheters, which was significantly lower in the "SOP group". Samples for microbiological diagnostics were taken much more often in the daytime, although storage of the probes did not lead to worse results. Concrete instructions enable adequate preanalytical handling of microbiological probes. However, we could not recognize substantial improvements probably due to a preexisting high process quality on the ICU. Microbiological diagnostics during the night shift has to be improved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INTRACEREBRAL HEMORRHAGE; INFECTIONS; OUTCOMES; GUIDELINE; LENGTH; antibiotic stewardship; microbiological diagnostics; neurocritical care; quality of results; standard operating procedure |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Innere Medizin I Medicine > Lehrstuhl für Neurochirurgie Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Jul 2022 09:27 |
| Last Modified: | 13 Jul 2022 09:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/45775 |
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