Walter, Nike and Rupp, Markus and Hierl, Katja and Koch, Matthias and Kerschbaum, Maximilian and Worlicek, Michael and Alt, Volker (2021) Long-Term Patient-Related Quality of Life after Knee Periprosthetic Joint Infection. JOURNAL OF CLINICAL MEDICINE, 10 (5): 907. ISSN , 2077-0383
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Background: We aimed to evaluate the impact of knee periprosthetic joint infection (PJI) by assessing the patients' long-term quality of life and explicitly their psychological wellbeing after successful treatment. Methods: Thirty-six patients with achieved eradication of infection after knee PJI were included. Quality of life was evaluated with the EQ-5D and SF-36 outcome instruments as well as with an ICD-10 based symptom rating (ISR) and compared to normative data. Results: At a follow-up of 4.9 +/- 3.5 years the mean SF-36 score was 24.82 +/- 10.0 regarding the physical health component and 46.16 +/- 13.3 regarding the mental health component compared to German normative values of 48.36 +/- 9.4 (p < 0.001) and 50.87 +/- 8.8 (p = 0.003). The mean EQ-5D index reached 0.55 +/- 0.33 with an EQ-5D VAS rating of 52.14 +/- 19.9 compared to reference scores of 0.891 (p < 0.001) and 68.6 +/- 1.1 (p < 0.001). Mean scores of the ISR revealed the psychological symptom burden on the depression scale. Conclusion: PJI patients still suffer from significantly lower quality of life compared to normative data, even years after surgically successful treatment. Future clinical studies should focus on patient-related outcome measures. Newly emerging treatment strategies, prevention methods, and interdisciplinary approaches should be implemented to improve the quality of life of PJI patients.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; quality of life; periprosthetic joint infection; revision arthroplasty; psychological outcomes |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Unfallchirurgie Medicine > Abteilung für Psychosomatische Medizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Jul 2022 12:03 |
| Last Modified: | 19 Jul 2022 12:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/45803 |
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