Weber, Andrea and Leitzmann, Michael F. and Sedlmeier, Anja M. and Baurecht, Hansjorg and Jochem, Carmen and Haferkamp, Sebastian and Baumeister, Sebastian E. (2021) Association between physical activity, grip strength and sedentary behaviour with incidence of malignant melanoma: results from the UK Biobank. BRITISH JOURNAL OF CANCER, 125 (4). pp. 593-600. ISSN 0007-0920, 1532-1827
Full text not available from this repository. (Request a copy)Abstract
Background Physical activity has been positively related to malignant melanoma. However, that association may be confounded by ultraviolet radiation (UV), a variable closely related to both outdoor physical activity and malignant melanoma. We examined physical activity, grip strength and sedentary behaviour in relation to risk of malignant melanoma, accounting for relevant confounders using data from a prospective cohort study. Methods In 350,512 UK Biobank participants aged 38-73 years at baseline, physical activity was assessed with a modified version of the International Physical Activity Questionnaire Short Form, grip strength was measured with a hand dynamometer, and sedentary behaviour was recorded with three specific questions. Multivariable hazard ratios (HR) and corresponding 95% confidence intervals (CI) were estimated using Cox proportional hazards regression. Results During 7 years of follow-up, 1239 incident malignant melanoma diagnoses were recorded. Physical activity and sedentary behaviour were unrelated to malignant melanoma (HRs 1.01 (95% CI 0.95-1.07) and 1.04 (95% CI 0.97-1.12), respectively), and the initially positive association with grip strength in the basic model (HR 1.23, 95% CI 1.08-1.40) was attenuated after full adjustment (HR 1.10, 95% CI 0.96-1.26). Conclusion Physical activity, grip strength and sedentary behaviour are not associated with malignant melanoma risk.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MUSCLE STRENGTH; RISK-FACTORS; CANCER; HEALTH; DIAGNOSIS; EXERCISE; WEIGHT; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie Medicine > Institut für Epidemiologie und Präventivmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Jul 2022 12:13 |
| Last Modified: | 19 Jul 2022 12:13 |
| URI: | https://pred.uni-regensburg.de/id/eprint/45850 |
Actions (login required)
 |
View Item |
