Girtner, Florian and Fritsche, Hans-Martin and Zeman, Florian and Huber, Toni and Haider, Maximilian and Pickl, Christoph and Burger, Maximilian and Mayr, Roman (2021) Randomized Crossover-Controlled Evaluation of Simultaneous Bilateral Transcutaneous Electrostimulation of the Posterior Tibial Nerve During Urodynamic Studies in Patients With Lower Urinary Tract Symptoms. INTERNATIONAL NEUROUROLOGY JOURNAL, 25 (4). pp. 337-346. ISSN 2093-4777, 2093-6931
Full text not available from this repository. (Request a copy)Abstract
Purpose: Transcutaneous tibial nerve stimulation (TTNS) has proven to be a valuable treatment option for various lower urinary tract conditions, such as overactive bladder syndrome and neurogenic detrusor overactivity. The aim of this study was to investigate acute changes in urodynamic parameters due to bilateral TTNS. Methods: Fifty-one patients (18-87 years; 61% female) with various lower urinary tract symptoms were enrolled in this study. They were single-blinded and randomly assigned to receive simultaneous bilateral TTNS either during their first urodynamic examination, followed by a second round using a placebo stimulation technique, or vice versa. Results: For subjects without signs of anatomical pathologies, the filling volume at the first desire to void (FDV) increased significantly by 54 mL (interquartile range [IQR], 26-81 mL; P <0.01) under the influence of TTNS compared to placebo. The maximum cystometric capacity increased by 41 mL (IQR, 10-65 mL; P = 0.02). The median micturition volume of patients with pathological postvoid residual volumes (>100 mL) increased by 76 mL compared to patients without urinary retention (IQR, 6-166 mL; P = 0.03). Conclusions: Compared to placebo, simultaneous bilateral TTNS showed significant improvements in bladder functioning, such as delayed FDV, increased maximum cystometric capacity, and reduced urinary retention. Patients with signs of anatomical pathologies did not seem to benefit from TTNS. Further studies need to be conducted to compare the effectiveness of bilateral versus unilateral TTNS.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEUROGENIC DETRUSOR OVERACTIVITY; STIMULATION; BLADDER; NEUROMODULATION; DYSFUNCTION; VALIDATION; WOMEN; Percutaneous tibial nerve stimulation; Overactive bladder; Transcutaneous neuromodulation; Tibial nerve stimu-lation; Lower urinary tract symptoms; Urodynamics |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Jul 2022 12:38 |
| Last Modified: | 19 Jul 2022 12:38 |
| URI: | https://pred.uni-regensburg.de/id/eprint/45891 |
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