Dobler, Daniel and Leitner, Michael and Moor, Natalija and Reiser, Oliver (2021) 2-Pyrone - A Privileged Heterocycle and Widespread Motif in Nature. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2021 (46). pp. 6180-6205. ISSN 1434-193X, 1099-0690
Full text not available from this repository. (Request a copy)Abstract
The 2-pyrone moiety can be found in a large number of natural products with a wide range of biological activities, including antibiotic, antifungal, cytotoxic, neurotoxic, phytotoxic, anti-inflammatory and cardiotonic effects. With its heterocyclic structure encompassing the chemical nature of conjugated dienes, lactones, Michael acceptors and arenes, it can undergo a great variety of transformations such as cycloadditions, ring-opening reactions, cross-couplings and lactamizations. Thus, 2-pyrones represent valuable synthetic precursors and worthwhile targets in organic, polymer, and medical chemistry. Owing to its exquisite chemical and physical properties, the synthesis and further transformations of 2-pyrones have attracted considerable attention over the past decade, showcasing transition metal and metal free strategies and using readily available starting materials, notably those stemming from renewable resources.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DIELS-ALDER REACTIONS; ELECTRONICALLY MATCHED 2-PYRONES; CATALYZED DECARBONYLATIVE ADDITION; H BOND FUNCTIONALIZATION; ONE-POT SYNTHESIS; ALPHA-PYRONES; METHYL-COUMALATE; STEREOSELECTIVE-SYNTHESIS; SELECTIVE SYNTHESIS; COUPLING REACTIONS; Cross-coupling reactions; Cycloaddition; 2-Pyrone; Ring-opening reactions; Synthetic methods |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser |
| Depositing User: | Petra Gürster |
| Date Deposited: | 20 Dec 2022 09:22 |
| Last Modified: | 20 Dec 2022 09:22 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46122 |
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