Menon, Rohit and Suss, Theresa and Oliveira, Vinicius Elias de Moura and Neumann, Inga D. and Bludau, Anna (2022) Neurobiology of the lateral septum: regulation of social behavior. TRENDS IN NEUROSCIENCES, 45 (1). pp. 27-40. ISSN 0166-2236, 1878-108X
Full text not available from this repository. (Request a copy)Abstract
Social interactions are essential for mammalian life and are regulated by evolutionary conserved neuronal mechanisms. An individual's internal state, experiences, and the nature of the social stimulus are critical for determining apt responses to social situations. The lateral septum (LS) - a structure of the basal forebrain - integrates abundant cortical and subcortical inputs, and projects to multiple downstream regions to generate appropriate behavioral responses. Although incoming cognitive information is indispensable for contextualizing a social stimulus, neuromodulatory information related to the internal state of the organism significantly influences the behavioral outcome as well. This review article provides an overview of the neuroanatomical properties of the LS, and examines its neurochemical (neuropeptidergic and hormonal) signaling, which provide the neuromodulatory information essential for fine-tuning social behavior across the lifespan.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SEX-SPECIFIC REGULATION; MATERNAL AGGRESSION; OXYTOCIN RECEPTOR; VASOPRESSIN RECEPTOR; INTERMALE AGGRESSION; HIPPOCAMPAL CA2; PREOPTIC AREA; BRAIN; NEURONS; STRESS |
| Subjects: | 500 Science > 590 Zoological sciences 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 29 Nov 2022 05:52 |
| Last Modified: | 29 Nov 2022 05:52 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46131 |
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