Kempa, Sally and Brix, Eva and Heine, Norbert and Hoesl, Vanessa and Strauss, Catharina and Eigenberger, Andreas and Brebant, Vanessa and Seitz, Stephan and Prantl, Lukas (2022) Autologous fat grafting for breast reconstruction after breast cancer: a 12-year experience. ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 305 (4). pp. 921-927. ISSN 0932-0067, 1432-0711
Full text not available from this repository. (Request a copy)Abstract
Purpose The aim of our study was to examine the surgical outcome and complications (efficiency) as well as the incidence of locoregional recurrence and distant metastases (oncological safety) in patients who underwent autologous fat grafting (AFG) of the breast following breast cancer surgery. Methods In our monocentric cohort study, retrospective and prospective data were collected from all consecutive patients who underwent AFG after breast cancer between 2008 and 2020; a total of 93 patients met the inclusion criteria. Results Our long-term results showed no increase in tumor recurrence and distant metastases in the studied collective when compared to the available literature. We observed 1 local recurrence (1.1%), 2 distant metastases (2.2%), and 1 tumor-related death (1.1%). There was a high degree of patient satisfaction; 67.12% of patients reported adequate satisfaction with autologous fat grafting. Conclusion Currently, to our knowledge, this is the study with the longest follow-up time (mean 6.7 years after AFG and 11.5 years after tumor resection). The results of our clinical study will contribute to improve evidence in the broad field of AFG, adipose stem cell and tumor research. Consistent with our study, the literature review shows a clear tendency of clinical trial results with a low incidence rate of tumor recurrence and metastasis following the use of AFG. AFG seems to be a safe procedure also after breast cancer treatment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ADIPOSE-TISSUE; CELLS; SAFETY; RISK; Autologous fat grafting; Transplantation; Breast Cancer; Reconstruction; Safety |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Frauenheilkunde) Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Aug 2022 08:49 |
| Last Modified: | 09 Aug 2022 08:49 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46203 |
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