Lang, Siegmund and Rupp, Markus and Hanses, Frank and Neumann, Carsten and Loibl, Markus and Alt, Volker (2021) Infections of the spine Pyogenic spondylodiscitis and implant-associated vertebral osteomyelitis. UNFALLCHIRURG, 124 (6). pp. 489-504. ISSN 0177-5537, 1433-044X
Full text not available from this repository. (Request a copy)Abstract
Pyogenic (unspecific) spondylodiscitis and implant-associated vertebral osteomyelitis (IAVO) are important diseases with the risk of neurological and septic complications. An early diagnosis is essential in which magnetic resonance imaging (MRI), histopathology and microbiological identification of the pathogen play key roles. The goals of conservative treatment in uncomplicated spondylodiscitis are antibiotic infection control and pain management. In the case of sepsis, neurological deficits, segmental instability or epidural abscesses surgical treatment of the infection with stabilization of the spine should be considered. In IAVO the formation of a mature biofilm represents the transition from acute to chronic infection. Acute infections can be treated by extensive debridement in combination with biofilm-active antibiotic treatment while retaining the implant. In chronic infections implant removal or exchange in combination with several weeks of antibiotic treatment is often necessary.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | INSTRUMENTATION; DIAGNOSIS; Treatment algorithm; Diagnostics; Antibiotic therapy; Surgery; Biofilm |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Unfallchirurgie Medicine > Abteilung für Krankenhaushygiene und Infektiologie Medicine > Notfallambulanz |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Aug 2022 08:50 |
| Last Modified: | 22 Aug 2022 08:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46329 |
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