Burger, Maximilian and Kamat, Ashish M. and McConkey, David (2021) Does Variant Histology Change Management of Non-muscle-invasive Bladder Cancer? EUROPEAN UROLOGY ONCOLOGY, 4 (3). pp. 510-514. ISSN , 2588-9311
Full text not available from this repository. (Request a copy)Abstract
A 52-yr-old man, 35 pack-year smoker, is diagnosed with two non-muscle-invasive urothelial tumors, pTa and pT1, the former upstaged to pT1 by a reference pathologist. Two possible treatment strategies include intravesical bacillus Calmette-Guerin (BCG) and/or primary or rescue cystectomy. The importance or even accurate existence of "variant histology" is put into perspective, and whether the reference pathologist's diagnosis of a micropapillary variant requires a real change in treatment strategy is considered. Patient summary: The reference urologist diagnosed two small bladder tumors as two different depths of infiltration: one as pTa and the other (slightly more severe) as pT1. Suspecting a variant, the reference urologist referred to a second pathologist, who upstaged the less severe tumor to T1, with both defined as micropapillary cancer. This presentation discusses removal of the bladder versus a trial of treatment with bladder preservation. (C) 2019 The Authors. Published by Elsevier B.V. on behalf of European Association of Urology.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MICROPAPILLARY UROTHELIAL CARCINOMA; CYSTECTOMY; Bacillus Calmette-Guerin; ERBB2; HER2; Micropapillary differentiation; Variant histology; Radical cystectomy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Urologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Sep 2022 08:02 |
| Last Modified: | 05 Sep 2022 08:02 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46573 |
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