Kerschbaum, Maximilian and Schurr, Leonhard Andreas and Riedl, Moritz and Mayr, Agnes and Weiss, Isabella and Klute, Lisa and Popp, Daniel and Pfeifer, Christian and Ernstberger, Antonio and Alt, Volker and Dendl, Lena Marie (2021) Clinical Value of CT for Differentiation between Ascites and Hemorrhage: An Experimental In-Vitro Study. JOURNAL OF CLINICAL MEDICINE, 10 (1): 76. ISSN , 2077-0383
Full text not available from this repository. (Request a copy)Abstract
Background: Abdominal trauma, leading to intra-abdominal bleeding, is a life-threatening condition that might need emergency surgical intervention. Sonography and Computed Tomography (CT) are most commonly used to detect free intra-abdominal fluid. This study investigates the accuracy of CT to distinguish between ascites and intra-abdominal hemorrhage. Methods: Ascites were collected during a clinical routine. Three serial dilutions, mixing ascites with whole blood samples of the patient and with two blood group identical donors, were prepared. Laboratory-chemical analysis and radiological evaluation using CT with measurement of average Hounsfield Units (HU) were performed. Results: Between ascites and whole blood as well as between ascites and the 1:1-ratio-samples, HU values differed significantly (p < 0.001). All further dilutions showed HU values with no significant difference compared to ascites (p >= 0.42). Whole blood showed significantly higher HU values than ascites and every step of the serial dilutions (p < 0.001). Measured HU values were also dependent on time and the exact point of measurement in the micro reaction vessels. Conclusions: In patients suffering from blunt abdominal trauma with preexisting ascites, HU values in CT imaging are not valid enough to exclude an acute hemorrhage.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | DIAGNOSTIC PERITONEAL-LAVAGE; ATTENUATION; ascites; abdominal injuries; trauma; hemorrhage; computed tomography |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Unfallchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 05 Sep 2022 08:07 |
| Last Modified: | 05 Sep 2022 08:07 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46589 |
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