Molecular mechanisms in dental follicle precursor cells during the osteogenic differentiation

Morsczeck, Christian (2015) Molecular mechanisms in dental follicle precursor cells during the osteogenic differentiation. HISTOLOGY AND HISTOPATHOLOGY, 30 (10). pp. 1161-1169. ISSN 0213-3911, 1699-5848

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Abstract

The discovery of dental stem cells received extensive attention because of its significance for the development of novel cellular therapies in dentistry. However, dental stem cells are also excellent for studies about cellular processes during dental tissue development or regeneration. Multipotent undifferentiated cells in the dental follicle (DFCs) are one example of dental stem cells. These cells have been used on studies about cellular processes during the differentiation into alveolar osteoblasts and cementoblasts. This review article summarizes current knowledge about the influence of signaling pathways, transcription factors and extracellular matrix proteins on the osteogenic differentiation of DFCs.

Item Type: Article
Uncontrolled Keywords: MESENCHYMAL STEM-CELLS; BONE MORPHOGENETIC PROTEIN; KINASE SIGNALING PATHWAYS; ZINC-FINGER PLZF; OSTEOBLAST DIFFERENTIATION; TRANSCRIPTION FACTOR; GENE-EXPRESSION; EXTRACELLULAR-MATRIX; IN-VITRO; DISTINCT ROLES; Dental follicle cells; Osteogenic differentiation; Transcription factors; Signaling pathways; Periodontium
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Mund-, Kiefer- und Gesichtschirurgie
Depositing User: Petra Gürster
Date Deposited: 26 Aug 2020 06:48
Last Modified: 26 Aug 2020 06:48
URI: https://pred.uni-regensburg.de/id/eprint/4659

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