Hintschich, Constantin A. and Niv, Masha Y. and Hummel, Thomas (2022) The taste of the pandemic-contemporary review on the current state of research on gustation in coronavirus disease 2019 (COVID-19). INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 12 (2). pp. 210-216. ISSN 2042-6976, 2042-6984
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Subjectively perceived impairment of taste is a common and distinct symptom of coronavirus disease 2019 (COVID-19). Large meta-analyses identified this symptom in approximately 50% of cases. However, this high prevalence is not supported by blinded and validated psychophysical gustatory testing, which showed a much lower prevalence in up to 26% of patients. This discrepancy may be due to misinterpretation of impaired retronasal olfaction as gustatory dysfunction. In addition, we hypothesized that COVID-19-associated hyposmia is involved in the decrease of gustatory function, as found for hyposmia of different origin. This indirect mechanism would be based on the central-nervous mutual amplification between the chemical senses, which fails in COVID-19-associated olfactory loss. However, further research is necessary on how severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) may directly impair the gustatory pathway as well as its subjective perception.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHEMICAL SENSES; SMELL; SENSITIVITY; DYSFUNCTION; CELLS; ageusia; COVID-19; gustation; smell; taste |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde |
| Depositing User: | Petra Gürster |
| Date Deposited: | 29 Nov 2022 06:16 |
| Last Modified: | 29 Nov 2022 06:16 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46645 |
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