Surgical treatment of focal cartilage defects in the knee Indications, techniques, modifications and results

Anders, Sven and Grifka, Joachim (2021) Surgical treatment of focal cartilage defects in the knee Indications, techniques, modifications and results. ZEITSCHRIFT FUR RHEUMATOLOGIE, 80 (9). pp. 855-867. ISSN 0340-1855, 1435-1250

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Abstract

The treatment strategies for focal cartilage damage in the knee are multifarious. For established procedures, such as microfracturing (MFX), autologous matrix-induced chondrogenesis (AMIC), osteochondral transplantation (OCT) and autologous chondrocyte transplantation (ACT), well-founded, partly comparative long-term studies and overlapping size-dependent differential indications are available. Innovative cell sources, the utilization of biological scaffolds as well as biologic agents and various combinations, have recently become the focus of scientific attention; however, high regulatory demands are restricting their use in Germany. The success of every procedure is dependent on the appropriate indications, the treatment of comorbidities, such as axis deviations or ligamentous instability, the surgeon's experience and an adequate follow-up treatment.

Item Type: Article
Uncontrolled Keywords: AUTOLOGOUS CHONDROCYTE IMPLANTATION; MATRIX-INDUCED CHONDROGENESIS; CLINICAL TISSUE REGENERATION; RANDOMIZED CONTROLLED-TRIAL; MESENCHYMAL STEM-CELLS; FOLLOW-UP; ARTICULAR-CARTILAGE; CHONDRAL DEFECTS; NEXT-GENERATION; GERMAN SOCIETY; Microfracturing; Autologous matrix-induced chondrogenesis; Osteochondral transplantation; Autologous chondrocyte transplantation; Allograft
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Orthopädie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Sep 2022 09:46
Last Modified: 07 Sep 2022 09:46
URI: https://pred.uni-regensburg.de/id/eprint/46778

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