Moellhoff, N. and Prantl, Lukas and Fritschen, Uv and Germann, G. and Giunta, R. E. and Kehrer, A. and Aung, T. and Zeman, Florian and Broer, P. N. and Heidekrueger, P. (2021) Uni-vs. bilateral DIEP flap reconstruction - A multicenter outcome analysis. SURGICAL ONCOLOGY-OXFORD, 38: 101605. ISSN 0960-7404, 1879-3320
Full text not available from this repository. (Request a copy)Abstract
Objective: Over the past decade numbers of bilateral mastectomy have increased steadily. As a result, bilateral breast reconstruction is gaining popularity. The presented study compares complications and outcomes of unilateral and bilateral DIEP free-flap breast reconstructions using the largest database available in Europe. Methods: Female breast cancer patients (n = 3926) receiving DIEP flap breast reconstructions (n = 4577 free flaps) at 22 different centers were included in this study. Free flaps were stratified into two groups: a unilateral(UL) and a bilateral- (BL) breast reconstruction group. Groups were compared with regard to surgical complications and free flap outcome. Results: Mean operative time was significantly longer in the BL group (UL: 285.2 +/- 107.7 vs. BL: 399.1 +/- 136.8 min; p < 0.001). Mean ischemia time was comparable between groups (p = 0.741). There was no significant difference with regard to total (UL 1.8% vs. BL 2.6%, p = 0.081) or partial flap loss (UL 1.2% vs. BL 0.9%, p = 0.45) between both groups. Rates of venous or arterial thrombosis were comparable between both groups (venous: UL 2.9% vs. BL 2.2%, p = 0.189; arterial: UL 1.8% vs. BL 1.2%, p = 0.182). However, significantly higher rates of hematoma at the donor and recipient site were observed in the UL group (donor site: UL 1.1% vs. BL 0.1%, p = 0.001; recipient site UL 3.9% vs. BL 1.7%, p < 0.001). Conclusions: The data underline the feasibility of bilateral DIEP flap reconstruction, when performed in a setting of specialized centers.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CONTRALATERAL PROPHYLACTIC MASTECTOMY; BREAST RECONSTRUCTION; PATIENT SATISFACTION; PERFORATOR FLAPS; FAMILY-HISTORY; CANCER; WOMEN; RISK; EFFICACY; STAGE; Breast reconstruction; Autologous; DIEP Flap; Bilateral |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 07 Sep 2022 09:51 |
| Last Modified: | 07 Sep 2022 09:51 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46795 |
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