Influence of Anxiety/Depression, Age, Gender and ASA on 1-Year Follow-Up Outcomes Following Total Hip and Knee Arthroplasty in 5447 Patients

Goetz, Julia Sabrina and Benditz, Achim and Reinhard, Jan and Schindler, Melanie and Zeman, Florian and Grifka, Joachim and Greimel, Felix and Leiss, Franziska (2021) Influence of Anxiety/Depression, Age, Gender and ASA on 1-Year Follow-Up Outcomes Following Total Hip and Knee Arthroplasty in 5447 Patients. JOURNAL OF CLINICAL MEDICINE, 10 (14): 3095. ISSN , 2077-0383

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Abstract

Introduction: There are many factors influencing the outcome after total joint arthroplasty (TJA). In particular, patient-related factors such as age, gender, ASA (American Society of Anesthesiologists), or preoperative anxiety/depression have become increasingly important. The aim of this study was to examine the association of these parameters with 1-year postoperative outcomes after total knee and total hip arthroplasty (TKA, THA). Methods: A retrospective cohort of 5447 TJA patients was evaluated by pre- and postoperative analysis of EQ-5D, EQ-VAS and WOMAC Score. Furthermore, major focus was put on the association between age, gender, ASA, preoperative anxiety/depression and outcome parameters. Results: 53.3% (2903/5447) of all patients were identified with anxiety/depression at time of surgery. In the analysis, patients without anxiety/depression showed statistically significantly (p < 0.05) better EQ-5D, EQ-VAS and WOMAC scores. In addition, patients with ASA 2 or 3 and age over 70 years showed statistically significantly (p < 0.01) worse EQ-5D and WOMAC scores. Gender did not influence the postoperative EQ-5D and WOMAC results, but men had significantly better EQ-VAS scores than women in this study. Conclusion: Preoperative anxiety/depression symptoms show worse clinical outcomes 1 year postoperatively after TJA. Other outcome-influencing factors are higher age and ASA 2 or 3. In the future, such patients should be identified, and as far as applicable, a treatment of anxiety/depression or comorbidities should be implemented preoperatively of the surgical procedure to improve clinical outcomes.

Item Type: Article
Uncontrolled Keywords: TOTAL JOINT ARTHROPLASTY; PREOPERATIVE ANXIETY; DEPRESSIVE SYMPTOMS; PAIN; PREDICT; EPIDEMIOLOGY; COMORBIDITY; SEVERITY; BENEFITS; DISEASE; anxiety; depression; knee arthroplasty (TKA); hip arthroplasty (THA); total joint arthroplasty (TJA); postoperative outcomes
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Orthopädie
Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Sep 2022 11:44
Last Modified: 07 Sep 2022 11:44
URI: https://pred.uni-regensburg.de/id/eprint/46813

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