Stuerznickel, Julian and Delsmann, Maximilian M. and Jungesblut, Oliver D. and Stucker, Ralf and Knorr, Christian and Rolvien, Tim and Kertai, Michael and Rupprecht, Martin (2021) Safety and performance of biodegradable magnesium-based implants in children and adolescents. INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 52 (8). pp. 2265-2271. ISSN 0020-1383, 1879-0267
Full text not available from this repository. (Request a copy)Abstract
Aims: Biodegradable magnesium-based alloy implants represent a promising option in orthopedic surgery, as the clinical outcomes have been reported to be comparable to those of titanium implants and no surgical interventions are required for removal. To date, little is known about the results of the use of these implants in children and adolescents. Therefore, the aim of the present study was to analyze the safety and performance of these implants in children and adolescents. Patients and Methods: Eighty-nine patients treated with magnesium-based implants for fracture stabilization, osteotomy and osteochondral refixation were analyzed; 38 were treated by osteosynthesis; 18, osteotomy; and 33, osteochondral refixation. The mean follow-up duration was 8.2 months (range, 1.5- 30 months). Clinical and radiographical follow-up examinations were performed at 4-8 weeks and 3-6 months, respectively, to evaluate implant performance and osseous consolidation. Results: Clinical outcomes were rated as good to very good in all patients. Radiolucent zones were apparent after surgery in all patients but were noted to decrease in size during the follow-up period. Revision surgery was necessary in 1 of 89 patients who had a highly unstable osteochondritis dissecans lesion of the knee. None of the magnesium-based implants required surgical removal. Conclusion: Magnesium-based implants in children and adolescents results in good clinical outcomes when used for fracture stabilization, osteotomy and osteochondral defect refixation. Future studies are needed to further analyze the significance of the transient appearance and temporal development of radiolucent zones in the growing skeleton as well as the long-term performance of these implants. (c) 2021 Elsevier Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | QUALITY-OF-LIFE; FRACTURES; REMOVAL; PATTERN; ALLOYS; SCREWS; Magnesium screws; Pediatrics; Osteosynthesis; Osteotomy; Osteochondral refixation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Kinder- und Jugendmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Sep 2022 05:28 |
| Last Modified: | 09 Sep 2022 05:28 |
| URI: | https://pred.uni-regensburg.de/id/eprint/46887 |
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