Barda, C. and Grafakou, M-E and Kalpoutzakis, E. and Heilmann, J. and Skaltsa, H. (2021) Chemical composition of Crepis foetida L. and C. rubra L. volatile constituents and evaluation of the in vitro anti-inflammatory activity of salicylaldehyde rich volatile fraction. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 96: 104256. ISSN 0305-1978, 1873-2925
Full text not available from this repository. (Request a copy)Abstract
The genus Crepis L. (Asteraceae) comprises more than 200 currently recognized species. Several studies have been conducted on non-volatile phytochemicals of Crepis spp., featuring mainly sesquiterpene lactones and phenolic derivatives. Nevertheless, no report has been made on assessing the volatile constituents of the genus. Therefore, the present study is the first report to the chemical composition of the volatile constituents of two odoriferous Crepis spp., namely C. foetida L. and C. rubra L. Flowers and stems with leaves volatiles were analysed separately by gas chromatography coupled with mass spectrometry. In total, 37 volatile compounds were detected. Salicylaldehyde, carvacrol and aliphatic hydrocarbons are the main components of both C. foetida fractions, however C. rubra flowers are characterized by the abundance of beta-sitosterol and eicosanoic acid, while the stems-leaves volatiles revealed to be more complex with hydrocarbons as main constituents. In addition, we investigated the salicylaldehyde rich volatile fraction for its in vitro activity on TNF-alpha induced ICAM-1 expression.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHEMOSYSTEMATIC MARKERS; CICHORIEAE; ASTERACEAE; PHENOLICS; Crepis; C; foetida; C; rubra; GC-MS; Volatile constituents |
| Subjects: | 500 Science > 540 Chemistry & allied sciences 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 01 Sep 2022 04:50 |
| Last Modified: | 01 Sep 2022 04:50 |
| URI: | https://pred.uni-regensburg.de/id/eprint/47102 |
Actions (login required)
![]() |
View Item |

