Impact of patients' gender on microvascular lower extremity reconstruction

Moellhoff, Nicholas and Broer, P. Niclas and Heidekrueger, Paul I. and Ninkovic, Milomir and Ehrl, Denis (2022) Impact of patients' gender on microvascular lower extremity reconstruction. JOURNAL OF PLASTIC SURGERY AND HAND SURGERY, 56 (1). pp. 47-52. ISSN 2000-656X, 2000-6764

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Abstract

The physiological differences between genders have significant implications for health and disease. With regard to microsurgery, results remain elusive as to whether male or female gender is an independent risk factor for free flap reconstruction. This study evaluated the impact of gender on outcomes of lower-extremity free-flap reconstructions. Within 7 years, 358 patients received 393 microvascular lower limb free flap reconstructions. The cases were divided into two groups according to patients' gender: male vs. female. Retrospective data analysis evaluated patients' demographics, perioperative details, surgical complications and flap outcomes over a 3-month follow-up period. Major and minor surgical complications, including total and partial flap loss, showed no significant differences between the investigated groups (p>.05). In addition, there was no significant difference with regard to the rate of surgical revision surgery, or the incidence of arterial and venous thrombosis (p>.05). Comparison of different flap types (fasciocutaneous ALT vs. gracilis muscle flaps) and type of anastomosis (end-to-end vs. end-to-side) also revealed no difference in outcomes in respect to gender. In conclusion, gender cannot be regarded as an independent risk factor for free flap reconstructions in patients with lower-extremity defects.

Item Type: Article
Uncontrolled Keywords: FREE-FLAP RECONSTRUCTIONS; RISK-FACTORS; PERSONALIZED MEDICINE; SEX STEROIDS; OUTCOMES; COMPLICATIONS; FAILURE; HEAD; PREVALENCE; MORTALITY; Gender; microsurgery; free flap; risk constellation; lower limb
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Plastische-, Hand- und Wiederherstellungschirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 23 Sep 2022 05:22
Last Modified: 23 Sep 2022 05:22
URI: https://pred.uni-regensburg.de/id/eprint/47898

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