Passweg, Jakob R. and Baldomero, Helen and Chabannon, Christian and Basak, Grzegorz W. and de la Camara, Rafael and Corbacioglu, Selim and Dolstra, Harry and Duarte, Rafael and Glass, Bertram and Greco, Raffaella and Lankester, Arjan C. and Mohty, Mohamad and de Latour, Regis Peffault and Snowden, John A. and Yakoub-Agha, Ibrahim and Kroeger, Nicolaus (2021) Hematopoietic cell transplantation and cellular therapy survey of the EBMT: monitoring of activities and trends over 30 years. BONE MARROW TRANSPLANTATION, 56 (7). pp. 1651-1664. ISSN 0268-3369, 1476-5365
Full text not available from this repository. (Request a copy)Abstract
Numbers of Hematopoietic cell transplantation (HCT) in Europe and collaborating countries continues to rise with 48,512 HCT in 43,581 patients, comprising of 19,798 (41%) allogeneic and 28,714 (59%) autologous, reported by 700 centers in 51 countries during 2019. Main indications were myeloid malignancies 10,764 (25%), lymphoid malignancies 27,895 (64%), and nonmalignant disorders 3173 (7%). A marked growth in CAR-T cellular therapies from 151 in 2017 to 1134 patients in 2019 is observed. This year's analyses focus on changes over 30 years. Since the first survey in 1990 where 143 centers reported 4234 HCT, the number has increased to 700 centers and 48,512 HCT. Transplants were reported in 20 countries in 1990, and 51, 30 years later. More than 800,000 HCT in 715,000 patients were reported overall. Next to the massive expansion of HCT technology, most notable developments include the success of unrelated donor and haploidentical HCT, an increase followed by decrease in the number of cord blood transplants, use of reduced intensity HCT in older patients, and the phenomenal rise in cellular therapy. This annual report of the European Society for Blood and Marrow Transplantation (EBMT) reflects current activity and highlights important trends vital for health care planning.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 27 Sep 2022 08:29 |
| Last Modified: | 27 Sep 2022 08:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48026 |
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