Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure -A clinical practice Guideline Level 3

Assmann, Alexander and Beckmann, Andreas and Schmid, Christof and Werdan, Karl and Michels, Guido and Miera, Oliver and Schmidt, Florian and Klotz, Stefan and Starck, Christoph and Pilarczyk, Kevin and Rastan, Ardawan and Burckhardt, Marion and Nothacker, Monika and Muellenbach, Ralf and Zausig, York and Haake, Nils and Groesdonk, Heinrich and Ferrari, Markus and Buerke, Michael and Hennersdorf, Marcus and Rosenberg, Mark and Schaible, Thomas and Koeditz, Harald and Kluge, Stefan and Janssens, Uwe and Lubnow, Matthias and Flemmer, Andreas and Herber-Jonat, Susanne and Wessel, Lucas and Buchwald, Dirk and Maier, Sven and Krueger, Lars and Fruend, Andreas and Jaksties, Rolf and Fischer, Stefan and Wiebe, Karsten and Hartog, Christiane S. and Dzemali, Omer and Zimpfer, Daniel and Ruttmann-Ulmer, Elfriede and Schlensak, Christian and Kelm, Malte and Ensminger, Stephan and Boeken, Udo (2022) Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure -A clinical practice Guideline Level 3. ESC HEART FAILURE, 9 (1). pp. 506-518. ISSN 2055-5822,

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Abstract

Aims Worldwide applications of extracorporeal circulation for mechanical support in cardiac and circulatory failure, which are referred to as extracorporeal life support (ECLS) or veno-arterial extracorporeal membrane oxygenation (va-ECMO), have dramatically increased over the past decade. In spite of the expanding use and the immense medical as well as socio-economic impact of this therapeutic approach, there has been a lack of interdisciplinary recommendations considering the best available evidence for ECLS treatment. Methods and Results In a multiprofessional, interdisciplinary scientific effort of all scientific societies involved in the treatment of patients with acute cardiac and circulatory failure, the first evidence- and expert consensus-based guideline (level S3) on ECLS/ECMO therapy was developed in a structured approach under regulations of the AWMF (Association of the Scientific Medical Societies in Germany) and under use of GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria. This article presents all recommendations created by the expert panel, addressing a multitude of aspects for ECLS initiation, continuation, weaning and aftercare as well as structural and personnel requirements. Conclusions This first evidence- and expert consensus-based guideline (level S3) on ECLS/ECMO therapy should be used to apply the best available care nationwide. Beyond clinical practice advice, remaining important research aspects for future scientific efforts are formulated.

Item Type: Article
Uncontrolled Keywords: REFRACTORY CARDIOGENIC-SHOCK; MEMBRANE-OXYGENATION; LIFE-SUPPORT; POSITION PAPER; ADULT PATIENTS; CARDIOPULMONARY-RESUSCITATION; NEUROLOGIC COMPLICATIONS; SURVIVAL; ORGANIZATION; ARREST; Extracorporeal life support (ECLS); Extracorporeal membrane oxygenation (ECMO); Cardiac and circulatory failure; Guideline; Recommendation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 27 Sep 2022 13:19
Last Modified: 27 Sep 2022 13:19
URI: https://pred.uni-regensburg.de/id/eprint/48096

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