Rothoerl, Ralf Dirk and Woertgen, Chris and Holzschuh, Matthias and Metz, Christoph and Brawanski, Alexander (1999) Rapid evaluation of S-100 serum levels. Case report and comparison to previous results. BRAIN INJURY, 13 (5). pp. 387-391. ISSN 0269-9052,
Full text not available from this repository.Abstract
The aim of this case report is to describe the time course of S-100 serum levels of a patient, after severe head injury, whose blood sample could be drawn very soon after injury. The results were compared to a group of patients in which a correlation between S-100 serum levels and outcome after traumatic brain injury could be demonstrated. Blood samples were taken on admission (mean 2.3 hours), 6, 12 and 24 hours after trauma and then every 24 hours up until and including the fifth day. The outcome was estimated on discharge using the Glasgow Outcome Scale. The S-100 serum level of the patient described in the case report with a favourable outcome had initially risen to 10.0 mu g/l and showed a rapid decline. In the previous group, patients with unfavourable outcome had a S-100 serum level of 7 mu g/l mean concerning the fuse probe (after 2.3 hours mean) compared to 1.5 mu g/l mean (after 2.23 hours mean) in patients with favourable outcome (p < 0.05). In comparison to the literature, there seems to be differences regarding the enzyme liberation in stroke and head injury. Therefore, S-100 serum levels need to be interpreted with regard to collection time and underlying pathology.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEURON-SPECIFIC ENOLASE; ISCHEMIC BRAIN-DAMAGE; CREATINE-KINASE BB; CEREBROSPINAL-FLUID; HEAD-INJURY; PROTEIN; INCREASES; STROKE; NSE; CSF; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Neurochirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 19 Oct 2022 13:20 |
| Last Modified: | 19 Oct 2022 13:20 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48262 |
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