Regression and epithelial hyperplasia after myopic photorefractive keratectomy in a human cornea

Lohmann, Chris P. and Reischl, Udo and Marshall, John (1999) Regression and epithelial hyperplasia after myopic photorefractive keratectomy in a human cornea. JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 25 (5). pp. 712-715. ISSN 0886-3350,

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Abstract

We present the histology of a cornea of a woman who had excimer laser photorefractive keratectomy (PRK) for myopia 6 months before she died in an accident. Preoperative spherical refraction was -6.00 diopters (D) with an astigmatism of -0.50 D. Six months postoperatively, refraction was -4.50 D. Slight corneal haze was noted at 1 and 3 months. The corneal histology showed marked epithelial hyperplasia in the center of the ablation zone without subepithelial deposition of newly synthesized collagen, proteoglycans, or both. The epithelial thickness was 38 mu m in the untreated area and 93 mu m in the center of the ablation. In conclusion, postoperative epithelial hyperplasia was responsible for regression after PRK in this eye. (C) 1999 ASCRS and ESCRS.

Item Type: Article
Uncontrolled Keywords: TOPICAL CORTICOSTEROIDS; HAZE; PRK;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 25 Oct 2022 09:27
Last Modified: 25 Oct 2022 09:27
URI: https://pred.uni-regensburg.de/id/eprint/48281

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