Synthesis of enantiomerically pure (-)-(S)-brevicolline

Mahboobi, Siavosh and Wiegrebe, Wolfgang and Popp, Alfred (1999) Synthesis of enantiomerically pure (-)-(S)-brevicolline. JOURNAL OF NATURAL PRODUCTS, 62 (4). pp. 577-579. ISSN 0163-3864,

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Abstract

(-)-(S)-Brevicolline (1) and related beta-carbolines were synthesized using an enantiomerically pure Michael-acceptor synthon (3). Subsequent Pictet-Spengler reaction afforded the tetrahydro-beta-carboline skeleton, which, in turn, was transformed to the beta-carboline by catalytic dehydrogenation.

Item Type: Article
Uncontrolled Keywords: MARINE ORIGIN;
Subjects: 600 Technology > 615 Pharmacy
Divisions: Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Nov 2022 14:06
Last Modified: 08 Nov 2022 14:06
URI: https://pred.uni-regensburg.de/id/eprint/48408

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