Kumar, Sunil and Mueller, Klaus (1999) Medicinal plants from Nepal; II. Evaluation as inhibitors of lipid peroxidation in biological membranes. JOURNAL OF ETHNOPHARMACOLOGY, 64 (2). pp. 135-139. ISSN 0378-8741,
Full text not available from this repository.Abstract
In an ethnopharmacological screening of selected Nepalese medicinal plants, the inhibitory effect on lipid peroxidation of 36 methanolic extracts of 28 different plant species were evaluated using bovine brain phospholipid liposomes as model membranes. The most potent inhibitor with an IC50 value of 0.93 mu g/ml was the extract obtained from the bark of Clerodendrum indicum. The extracts obtained from Aglaia roxburghiana fruits, Euonymus pendulus barks and Emblica officinalis fruits were also active and inhibited lipid peroxidation with IC50 values of 10, 12 and 13 mu g/ml, respectively. The most active extracts were from indigenous plants traditionally used to treat inflammatory diseases. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 5-LIPOXYGENASE; RADICALS; lipid peroxidation; antioxidant activity; Nepalese plants; traditional medicine |
| Subjects: | 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Nov 2022 11:20 |
| Last Modified: | 22 Nov 2022 11:20 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48550 |
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