Krämer, Bernhard K. and Schweda, Frank and Riegger, Günter A. J. (1999) Diuretic treatment and diuretic resistance in heart failure. AMERICAN JOURNAL OF MEDICINE, 106 (1). pp. 90-96. ISSN 0002-9343, 1555-7162
Full text not available from this repository.Abstract
Diuretic therapy decreases capillary wedge pressure and improves New York Heart Association (NYHA) functional class both in acute and chronic heart failure. In advanced symptomatic heart failure, loop diuretics are generally necessary to improve symptoms of congestion. Diuretic resistance in the edematous patient has been defined as a clinical state in which diuretic response is diminished or lost before the therapeutic goal of relief from edema has been reached. The major causes of diuretic resistance are functional renal failure (prerenal azotemia), hyponatremia, altered diuretic pharmacokinetics, and sodium retention caused by counterregulatory mechanisms intended to reestablish the effective arterial blood volume. Therapeutic approaches to combat diuretic resistance include restriction of fluid and sodium intake, use of angiotensin-converting-enzyme (ACE) inhibitors, changes in route (oral, intravenous) and timing (single dose, multiple doses, continuous infusion) of diuretic therapy, and use of diuretic combinations. Am J Med. 1999;106:90-96. (C) 1999 by Excerpta Medica, Inc.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | FUROSEMIDE-INDUCED NATRIURESIS; CONVERTING-ENZYME-INHIBITION; CONTINUOUS-INFUSION; RENAL-FUNCTION; LOOP DIURETICS; MYOCARDIAL-INFARCTION; SODIUM RETENTION; CARDIAC-FUNCTION; PLASMA HORMONES; HYPERTENSION |
| Subjects: | 500 Science > 570 Life sciences 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Frank Schweda |
| Depositing User: | Petra Gürster |
| Date Deposited: | 16 May 2024 07:53 |
| Last Modified: | 16 May 2024 07:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48594 |
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