Is there seasonal periodicity in the prevalence of Helicobacter pylori?

Raschka, Christoph and Schorr, Wolfgang and Koch, Horst J. (1999) Is there seasonal periodicity in the prevalence of Helicobacter pylori? CHRONOBIOLOGY INTERNATIONAL, 16 (6). pp. 811-819. ISSN 0742-0528,

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Abstract

The objective of the present study was to evaluate seasonal periodicity in the prevalence of Helicobacter pylori. A prospective study was performed on 1076 consecutive patients who were investigated in our hospital over a 3-year span because of epigastric complaints. Our findings-indicate a significant accumulation of positive Helicobacter pylori tests, in October.:Gastric acidity, gender, and age did not influence Helicobacter pylori infection significantly. There was no significant correlation between potential seasonal influence on the diagnosis of ulcer disease and the seasonal fluctuation of Helicobacter pylori infection. The seasonality was confirmed by cosinor analysis for the absolute frequencies of H. pylori infections and also for the number of cases positive for H. pylori per number of presenting patients per month. A seasonal concept of a sensitivity threshold for positive Helicobacter pylori testing is introduced, taking into account such factors as immune system, nutrition, and medication status.

Item Type: Article
Uncontrolled Keywords: DUODENAL-ULCER; PEPTIC-ULCER; INFECTION; EPIDEMIOLOGY; DISEASE; FLUCTUATIONS; Helicobacter pylori; prevalence; seasonal periodicity; sensitivity threshold
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Nov 2022 10:26
Last Modified: 29 Nov 2022 10:26
URI: https://pred.uni-regensburg.de/id/eprint/48626

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