Mahboobi, Siavosh and Pongratz, Herwig (1999) Synthesis of 2 '-amino-3 '-methoxyflavone (PD 98059). SYNTHETIC COMMUNICATIONS, 29 (10). pp. 1645-1652. ISSN 0039-7911,
Full text not available from this repository. (Request a copy)Abstract
2'-Amino-3'-methoxyflavone selectively blocks the activity of MAP kinase kinase (MEK) by inhibiting the activation of MAP kinase. This paper reports a straightforward synthesis of PD 98059 and 2-tert-butyl-8-methoxy-1,4-dihydro-quinolin-4-one.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GROWTH-FACTOR; ACTIVATION; DESENSITIZATION; INHIBITOR; |
| Subjects: | 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Dec 2022 07:27 |
| Last Modified: | 06 Dec 2022 07:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48744 |
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