Strehl, R. and Trautner, V. and Kloth, S. and Minuth, Will W. (1999) Existence of a dense reticular meshwork surrounding the nephron inducer in neonatal rabbit kidney. CELL AND TISSUE RESEARCH, 298 (3). pp. 539-548. ISSN 0302-766X,
Full text not available from this repository. (Request a copy)Abstract
While more and more humoral factors involved in nephrogenesis are being discovered, there is no detailed knowledge of the morphological structures at the interface of the nephron inducer and the surrounding mesenchyme. For that reason we examined this area in the cortex of neonatal rabbit kidneys by scanning electron-microscopical and transmission electron-microscopical techniques. Our interest was focused on the basal aspect of the collecting duct ampulla and the surrounding competent mesenchyme, where morphogenic signals are to be exchanged during nephron induction. Close contact between these two tissues involved in nephrogenesis is assumed to allow direct cellular contact or diffusion of soluble factors across a short distance. Our data, however, show the presence of a dense fibrillar meshwork around the collecting duct ampulla, spatially separating the inducer and the competent mesenchyme during nephron induction.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | COLLECTING DUCT EPITHELIUM; METANEPHRIC MESENCHYME; TARGETED DISRUPTION; GROWTH-FACTOR; MOUSE; NEPHROGENESIS; CELLS; PRINCIPAL; INDUCTION; INTERFACE; kidney; collecting duct; ampulla; development; basement membrane; scanning electron microscopy; transmission electron microscopy; rabbit (New Zealand) |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Molekulare und zelluläre Anatomie > Prof. Dr. Will Minuth |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 Dec 2022 10:44 |
| Last Modified: | 06 Dec 2022 10:44 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48776 |
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