Asymmetric aminohydroxylation of heteroaromatic acrylates

Raatz, Dirk and Innertsberger, Clara and Reiser, Oliver (1999) Asymmetric aminohydroxylation of heteroaromatic acrylates. SYNLETT (12). pp. 1907-1910. ISSN 0936-5214,

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Abstract

N-, S- and O-heteroaromatic acrylates were amino-hydroxylated with generally high regio- and enantioselectivity. While pyridylacrylates are not amenable towards this process, the corresponding N-oxides proved to be a useful substitute, allowing the access to biologically important pyridine substituted taxol(TM) side chain analogs.

Item Type: Article
Uncontrolled Keywords: ENANTIOSELECTIVE SYNTHESIS; SUBSTITUTED STYRENES; SIDE-CHAIN; DIHYDROXYLATION; AMINATION; OLEFINS; ROUTE; aminohydroxylations; amino acids; asymmetric catalysis; taxol (TM) (paclitaxel); pyridines
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Dec 2022 14:03
Last Modified: 06 Dec 2022 14:03
URI: https://pred.uni-regensburg.de/id/eprint/48820

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