Mahboobi, Siavosh and Dove, Stefan and Kuhr, S. and Pongratz, Herwig (1999) Synthesis of arcyriarubine regioisomers by Pd(0)-catalysis or via lithiated indole derivatives - conformational analysis by semiempirical and X-ray methods. PHARMAZIE, 54 (11). pp. 820-827. ISSN 0031-7144,
Full text not available from this repository. (Request a copy)Abstract
Regioisomers of arcyriarubines were synthesized by the reaction of N-protected indoles with dibromomaleimide either in the presence of a Pd(0)-catalyst or n-BuLi. Methods for N-alkylation of these bisindolylmaleimides and deprotection of the indole-N are described. The structure of the bisindolylmaleimide 11 was studied by semiempiric quantum-chemical calculations, the structure of its derivative 14b was ascertained by X-ray analysis.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PROTEIN-KINASE-C; SELECTIVE INHIBITOR; POTENT; REBECCAMYCIN; UCN-01; |
| Subjects: | 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Dec 2022 09:56 |
| Last Modified: | 13 Dec 2022 09:56 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48900 |
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