Anesthesia management in implantation of baroreceptor stimulators

Werner, T. and Lebar, L. and Wittmann, S. and Keyser, A. and Fischer, M. and Schmidli, J. and Graf, B. M. and Zausig, Y. A. (2015) Anesthesia management in implantation of baroreceptor stimulators. ANAESTHESIST, 64 (9). pp. 683-688. ISSN 0003-2417, 1432-055X

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Abstract

Baroreceptor stimulators are novel implantable devices that activate the carotid baroreceptor reflex. This results in a decrease in activity of the sympathetic nervous system and inhibition of the renin-angiotensin-aldosterone system. In patients with drug-resistant hypertension, permanent electrical activation of the baroreceptor reflex results in blood pressure reduction and cardiac remodeling. For correct intraoperative electrode placement at the carotid bifurcation, the baroreceptor reflex needs to be activated several times. Many common anesthetic agents, such as inhalation anesthetics and propofol dampen or inhibit the baroreceptor reflex and complicate or even prevent successful placement. Therefore, a specific anesthesia and pharmacological management is necessary to ensure successful implantation of baroreceptor reflex stimulators.

Item Type: Article
Uncontrolled Keywords: BAROREFLEX ACTIVATION THERAPY; SINUS NERVE-STIMULATION; HIGH BLOOD-PRESSURE; RESISTANT HYPERTENSION; HEART-RATE; ARTERIAL-HYPERTENSION; SURGICAL TECHNIQUE; FEASIBILITY TRIAL; UNITED-STATES; HUMANS; Electric stimulation therapy; Carotid sinus; Anesthesia; Baroreceptor reflex; Hypertension
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Innere Medizin II
Depositing User: Dr. Gernot Deinzer
Date Deposited: 11 Jun 2019 13:51
Last Modified: 11 Jun 2019 13:51
URI: https://pred.uni-regensburg.de/id/eprint/4893

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