Framme, Carsten and Dietrich, Joerg and Lohmann, Chris P. and Sachs, Helmut G. (1999) Eye involvement in circumscript cutaneous sclerosis - manifestation of borreliosis? KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 215 (4). pp. 258-262. ISSN 0023-2165, 1439-3999
Full text not available from this repository.Abstract
Background The circumscript cutaneous sclerosis is an inflammato-edematous erythema of the skin, usually leading to a plaque-like sclerosis and cutaneous atrophy. The etiology of this disease remains unknown, but some authors presume a systemic infection with Borrelia burgdorferi as the underlying pathological condition. Patient We present a case of a 66-year-old male patient who suffered from episcleritis of his left eye. Funduscopy showed an unilateral papillary edema. Visual acuity was 1.0. The patient had multiple erythemata of the skin of the body-trunk and the arms. On histological examination the lesions were compatible with circumscript sclerosis. Neurological examination was normal. Brain imaging (MRI), CSF examination and serology showed no pathological findings, although the patient presented with raised antibodies against Borrelia burgdorferi (IgG positive, IGM negative). Intravenous antibiotic treatment and topical steroids for three weeks resulted in a complete recovery of the scleritis, but had no effect on the papillary edema. Conclusion Inflammatory pathological findings of the eye can be associated with circumscript sclerosis, a disease, that is normally limited to the skin. The pathological mechanism remains unclear. The presumption of an underlying borreliosis could not be confirmed in this case.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | POLYMERASE CHAIN-REACTION; ACRODERMATITIS CHRONICA ATROPHICANS; LOCALIZED SCLERODERMA MORPHEA; LYME-DISEASE; ET-ATROPHICUS; BURGDORFERI INFECTION; SKIN-LESIONS; NO EVIDENCE; ERYTHEMA MIGRANS; DNA; episcleritis; papillitis; circumscript sclerosis; borreliosis |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Augenheilkunde Medicine > Lehrstuhl für Neurologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Dec 2022 15:36 |
| Last Modified: | 20 Dec 2022 15:36 |
| URI: | https://pred.uni-regensburg.de/id/eprint/48964 |
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