Becker, Georg and Berg, Daniela and Rausch, Wolf-Dieter and Lange, Klaus W. and Riederer, Peter and Reiners, Karlheinz (1999) Increased tissue copper and manganese content in the lentiform nucleus in primary adult-onset dystonia. ANNALS OF NEUROLOGY, 46 (2). pp. 260-263. ISSN 0364-5134, 1531-8249
Full text not available from this repository.Abstract
We analyzed trace metals in frozen brain tissue of several subcortical nuclei from 3 patients with primary adult-onset dystonia and 10 control subjects. Copper levels were significantly increased in the globus pallidus and putamen of patients with dystonia. A slight increase In manganese content was identified in the putamen and thalamus of patients with dystonia. Our findings shaw for the first time an accumulation of trace metals in the lentiform nuclei in patients with primary dystonia, which may play a pathogenetic role in primary dystonia and may explain recent ultrasound and magnetic resonance imaging findings.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | IDIOPATHIC DYSTONIA; RECEPTOR; IONS; RAT; |
| Subjects: | 100 Philosophy & psychology > 150 Psychology |
| Divisions: | Human Sciences > Institut für Psychologie > Lehrstuhl für Psychologie III (Biologische, Klinische und Rehabilitationspsychologie) - Prof. Dr. Klaus W. Lange |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 11 Jan 2023 09:48 |
| Last Modified: | 11 Jan 2023 09:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/49072 |
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