Nucleoid structure and partition in Methanococcus jannaschii: An Archaeon with multiple copies of the chromosome

Malandrin, Laurence and Huber, Harald and Bernander, Rolf (1999) Nucleoid structure and partition in Methanococcus jannaschii: An Archaeon with multiple copies of the chromosome. GENETICS, 152 (4). pp. 1315-1323. ISSN 0016-6731, 1943-2631

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Abstract

We measured different cellular parameters in the methanogenic archaeon Methanococcus jannaschii. In exponential growth phase, the cells contained multiple chromosomes and displayed a broad variation in size and DNA content. In most cells, the nucleoids were organized into a thread-like network, although less complex structures also were observed. During entry into stationary phase, chromosome replication continued to termination while no new rounds were initiated: the cells ended up with one to five chromosomes per cell with no apparent preference for any given DNA content. Most cells in stationary phase contained more than one genome equivalent. Asymmetric divisions were detected in stationary phase, and the nucleoids were found to be significantly more compact than in exponential phase.

Item Type: Article
Uncontrolled Keywords: COMPLETE GENOME SEQUENCE; THERMOPHILIC ARCHAEA; BACTERIAL-DNA; CELL-CYCLE; ACID; METHANOGEN; HYPOTHESIS; ORIGIN;
Subjects: 500 Science > 570 Life sciences
Divisions: Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Mikrobiologie (Archaeenzentrum)
Depositing User: Dr. Gernot Deinzer
Date Deposited: 11 Jan 2023 10:24
Last Modified: 11 Jan 2023 10:24
URI: https://pred.uni-regensburg.de/id/eprint/49086

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