Meister, Adolf and Bernhardt, Guenther and Christoffel, Volker and Buschauer, Armin (1999) Antispasmodic activity of Thymus vulgaris extract on the isolated guinea-pig trachea: Discrimination between drug and ethanol effects. PLANTA MEDICA, 65 (6). pp. 512-516. ISSN 0032-0943,
Full text not available from this repository. (Request a copy)Abstract
The effect of an extract of Thymus vulgaris on induced spasms was investigated on guinea-pig trachea preparations. By the experimental setup used, effects of ethanol as the vehicle could be differentiated from the activity of the herbal constituents. The extract reversibly and concentration-dependently antagonized the contraction of the Musculus transversus tracheae, provoked by four different spasmogens (BaCl2, carbachol, histamine, prostaglandin F-2 alpha). The degree of the antispasmodic activity was dependent on the individual spasmogen with prostaglandin F-2 alpha being most efficiently antagonized.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; Thymus vulgaris; Lamiaceae; guinea-pig trachea; antispasmodic activity; ethanol |
| Subjects: | 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 11 Jan 2023 15:29 |
| Last Modified: | 11 Jan 2023 15:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/49106 |
Actions (login required)
 |
View Item |
