3D MRI of the membranous labyrinth - An age related comparison of MR findings in patients with labyrinthine fibrosis and in persons without inner ear symptoms

Held, Paul and Fellner, C. and Fellner, F. and Graf, S. and Seitz, J. and Strutz, J. (1998) 3D MRI of the membranous labyrinth - An age related comparison of MR findings in patients with labyrinthine fibrosis and in persons without inner ear symptoms. JOURNAL OF NEURORADIOLOGY, 25 (4). pp. 268-274. ISSN 0150-9861, 1773-0406

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Abstract

Purpose: We compared MRI of the membranous labyrinth in patients with chronic non-neoplastic inner ear disease and MR signs of labyrinthine fibrosis and controls depending on their age, in order to establish whether there were any MR differences regarding patient age groups, control age groups and between the patients and controls themselves. Materials and method: Clinical ENT examinations as well as a T2* weighted 3D CISS (Constructive interference in Steady State) sequence with a slice thickness of 0.7 mm were performed. Our collective was subdivided as follows: 0-19 years (10 controls, 3 patients with chronic non-neoplastic inner car disease), 20-49 years (55 controls, 8 patients), 50 years and older (40 controls, 22 patients). Detectability of labyrinthine structures (e.g. cochlea, vestibule, semicircular canals) and filling defects were evaluated. Results: In the 3 age-groups of the control collective no significant differences were observed in the membranous labyrinth. However differences concerning labyrinthine detectability emerged between controls and patients in both the 20-49 years and 50 years and older age groups. In the patient collective the 3 age groups showed no significant discrepancy in the mean number of lesions. Conclusion: Filling defects of the membranous labyrinth on 3D CISS MR images are pathological even in older persons. We would therefore recommend high resolution T2* weighted MRI in the case of suspected labyrinthine fibrosis.

Item Type: Article
Uncontrolled Keywords: SPIN-ECHO; PATHOLOGY; MRI; 3D CISS; membranous labyrinth; labyrinthine fibrosis; inner ear
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde
Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 21 Feb 2023 07:41
Last Modified: 21 Feb 2023 07:41
URI: https://pred.uni-regensburg.de/id/eprint/49306

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