Altmann, M. M. and Wrede, C. E. and Peetz, D. and Hoehne, M. and Stroszczynski, C. and Herold, T. (2015) Age-Dependent D-dimer Cut-off to Avoid Unnecessary CT-Exams for Ruling-out Pulmonary Embolism. ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 187 (9). pp. 795-800. ISSN 1438-9029, 1438-9010
Full text not available from this repository. (Request a copy)Abstract
Purpose: To evaluate the effect of an age-dependent D-Dimer cut-off in patients who underwent a computed tomography pulmonary angiogram (CTPA) for suspected pulmonary embolism (PE) Material and Methods: Retrospective application of an age-dependent D-dimer cut-off (age/100 in patients aged over 50) in 530 consecutive patients, both in-and outpatients, aged over 18, who underwent CTPA for suspected PE according to the guidelines. Results: The application of an age-dependent D-dimer cut-off showed a now negative test-result in 17 of 530 patients (3.2 %). The proportion was 4.1 % (17 of 418) in patients aged over 50. None of these 17 cases was diagnosed with PE in CTPA, the false-negative rate was 0 %. The effect could be seen in outpatients (14 of 377 [3.7 %]) as well as in inpatients( 3 of 153 [2.0 %]) with no statistically significant difference (p > 0.05). Conclusion: The application of an age-dependent D-dimer cut-off as part of the guidline-based algorithm for suspected PE reduced the number of necessary CTPA in outpatients as well as in inpatients.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | VENOUS THROMBOEMBOLISM; COMPUTED-TOMOGRAPHY; OLDER PATIENTS; DIAGNOSIS; EXCLUSION; RULE; METAANALYSIS; PROBABILITY; ANGIOGRAPHY; PERFORMANCE; embolism/thrombosis; thorax; CT-angiography; vascular |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 12 Jun 2019 13:48 |
| Last Modified: | 12 Jun 2019 13:48 |
| URI: | https://pred.uni-regensburg.de/id/eprint/4935 |
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