Brunner, Henri and Tracht, Torsten (1998) Asymmetric catalysis. Part 128: Diastereomeric rhodium(I) complexes in the enantioselective hydrogenation of ketopantolactone. TETRAHEDRON-ASYMMETRY, 9 (21). pp. 3773-3780. ISSN 0957-4166
Full text not available from this repository.Abstract
In the hydrogenation of ketopantolactone, new rhodium complexes bearing (R,R)-diop and various bidentate chiral N,N' co-ligands with (R)- or (S)-configuration were used. On the one hand, the N,N' co-ligands consist of pyrroleimines, which derive from (R)- and (S)-1-phenylethylamine, (R)- and (S)-1-cyclohexylethylamine land benzylamine), and on the other hand of pyrroleoxazolines and pyridineimines. Stereoselectivities of 31-33% ee for (R)-pantolactone were achieved using related compounds (RR-R) and (RR-S), respectively, with no double stereoselectivity being observed. It is assumed that during catalysis the pyrroleimines bind in a monodentate way at the sixth coordination site of the rhodium atom by the pyrrole nitrogen with the imine nitrogen carrying the different chiral substituents far away from the rhodium atom. Monodentate deltacyclane phosphanes, chloro ligands or solvent molecules, bound at the sixth coordination site of the catalyst, led to widely differing enantioselectivities in the ketopantolactone hydrogenation. (C) 1998 Elsevier Science Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | CHIRAL METAL-COMPLEXES; ACTIVATED KETO COMPOUNDS; PHOSPHINO GROUPS; LIGANDS; PYRROLIDINEBISPHOSPHINES; DIPHOSPHINE; REDUCTION |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Anorganische Chemie > Alumni or Retired Professors > Prof. Dr. Henri Brunner |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Feb 2023 05:29 |
| Last Modified: | 23 Feb 2023 05:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/49358 |
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