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Full text not available from this repository.Abstract
Background: Little is known about the sensitivity, specificity, and predictive values of transabdominal ultrasonographic (US) findings in a teaching hospital setting. Methods: We carried out a prospective study including 227 patients with symptoms suggestive of inflammatory bowel disorder. The Picker 9200 CS equipment (5-mHz curved-array probe) was used to obtain bowel images. Gastrointestinal endoscopy, enteroclysis, bowel enema, computed tomography scan, or bowel surgery was used as reference. Results: Of 227 patients, 168 had pathologic findings of the bowel as final diagnosis. The overall sensitivity of US was 76%, whereas the positive predictive value was 98%. Overall specificity was 95%. The negative predictive value for bowel disorders was only 58%, since US missed pathologic findings in 48 patients. Subgroup analysis showed a sensitivity of 84% for Crohn's disease, 66% for ulcerative colitis, 46% for bowel tumors, and 60% for diverticulitis. Topographic comparisons showed that US detected inflammatory bowel-wall alterations preferentially in the terminal ileum and colon, whereas abnormalities in the duodenum, jejunum, and rectum were frequently missed (sensitivity, 10%-20%). Conclusions: Positive US findings are useful for the diagnosis of bowel processes. US is highly predictive albeit not disease-specific. Negative US examinations, however, do not exclude pathologic bowel processes. A topographic location of pathologic US findings is mostly confined to the colon.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ACUTE COLONIC DIVERTICULITIS; CROHNS-DISEASE; ACUTE APPENDICITIS; DIFFERENTIAL-DIAGNOSIS; SONOGRAPHIC DIAGNOSIS; CLINICAL-SIGNIFICANCE; INFLAMMATORY DISEASE; LARGE-INTESTINE; ULTRASONOGRAPHY; WALL; abdominal computed tomography; bowel-wall thickness; endoscopy; enteroclysis; inflammatory bowel disorders; target sign; transabdominal ultrasonography |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie Medicine > Lehrstuhl für Innere Medizin I Medicine > Lehrstuhl für Pathologie Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 18 Apr 2023 10:27 |
| Last Modified: | 18 Apr 2023 10:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/49406 |
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