Mycobacterium bohemicum sp. nov., a new slow-growing scotochromogenic mycobacterium

Reischl, Udo and Emler, Stefan and Horak, Zdenek and Kaustova, Jarmila and Kroppenstedt, Reiner M. and Lehn, Norbert and Naumann, Ludmila (1998) Mycobacterium bohemicum sp. nov., a new slow-growing scotochromogenic mycobacterium. INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 48 (4). pp. 1349-1355. ISSN 0020-7713

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Abstract

A new, slow-growing, scotochromogenic mycobacterium was isolated from sputum of a 53-year-old patient with Down's syndrome suffering from tuberculosis. Growth occurred at temperatures between 25 and 40 degrees C with an optimum at 37 degrees C. This strain had surprisingly few enzymic activities (only positive for 68 degrees C heat-stable catalase and weakly positive for urease) and was sensitive to prothionamide, cycloserine, clarithromycin, gentamicin and amikacin but showed resistance to isoniazid, streptomycin. ethambutol, rifampin and ciprofloxacin. These characteristics assign this organism to a novel mycobacterial species characterized by a unique 16S rDNA nucleotide sequence. The name Mycobacterium bohemicum sp. nov. is proposed for this new, slow-growing, scotochromogenic mycobacterium. The type strain is DSM 44277(T).

Item Type: Article
Uncontrolled Keywords: PERFORMANCE LIQUID-CHROMATOGRAPHY; THIN-LAYER CHROMATOGRAPHY; DEOXYRIBONUCLEIC-ACID; DNA; IDENTIFICATION; LYMPHADENITIS; EXTRACTION; BACTERIA; Mycobacterium bohemicum sp. nov.; 16S rDNA sequence; phylogenetic tree
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Dr. Gernot Deinzer
Date Deposited: 16 Feb 2023 06:30
Last Modified: 16 Feb 2023 06:30
URI: https://pred.uni-regensburg.de/id/eprint/49460

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