Ultrathin cellulose-based layers for detection of single antigen molecules

Löscher, Frank and Ruckstuhl, Thomas and Seeger, Stefan (1998) Ultrathin cellulose-based layers for detection of single antigen molecules. ADVANCED MATERIALS, 10 (13). pp. 1005-1009. ISSN 0935-9648, 1521-4095

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Abstract

The covalent immobilization of antibodies using non-amphiphilic alkylated cellulose films is described-the Figure shows the antibodies attached to the film via imino bonds. Rapid detection of a specific antibody-antigen reaction is demonstrated as is single-molecule detection. Thus biochemical surfaces prepared in this way have great potential as ultrasensitive bio- and immunosensors.

Item Type: Article
Uncontrolled Keywords: LASER-INDUCED FLUORESCENCE; OPTICAL-DETECTION; SPECTROSCOPY; IMMOBILIZATION; IMMUNOSENSORS; PHYCOERYTHRIN; ABSORPTION; FILMS
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 16 Feb 2023 09:08
Last Modified: 16 Feb 2023 09:08
URI: https://pred.uni-regensburg.de/id/eprint/49507

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