Kaiser, Alexander and Wiegrebe, Wolfgang (1998) 1,3-Diphenylpropane-1,3-diamines XII. A novel approach to stereodefined oximes and oxime ethers of monothioketalized 1,3-diketones and their conversion to 3-aminooximes. MONATSHEFTE FUR CHEMIE, 129 (8-9). pp. 937-952. ISSN 0026-9247, 1434-4475
Full text not available from this repository.Abstract
Mono-O,O- and mono-S,S-ketals of 1,3-diphenylpropane-1,3-diones react with hydroxylamine hydrochloride and O-methylhydroxylamine hydrochloride affording mixtures of (E/Z) isomers which are hard to separate or an even unseparable. Isomerically pure oximes and O-methyloximes, however, are obtained either from 2-lithiated 1,3-dithianes and alpha-halogeno-oximes and alpha-halogeno-oxime ethers, resp., or from lithiated oxime ethers and dithienium salts. Reduction, acetylation, hydrolysis of the ketal increment, and oximation afford 3-amino-oximes which are precursors of 1,3-diphenylpropane-1,3-diamines.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ANTI; KETONES; AZOLES; 1,3-diphenylpropane-1,3-diamines; monoketalized 1,3-diones; lithiated 1,3-dithianes; alpha-halogeno-oximes; alpha-halogeno-oxime ethers; dithienium salts; lithiated oxime ethers |
| Subjects: | 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 23 Feb 2023 10:01 |
| Last Modified: | 23 Feb 2023 10:01 |
| URI: | https://pred.uni-regensburg.de/id/eprint/49644 |
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