Krbavcic, Ales and Pecar, Slavko and Schara, M. and Mueller, Klaus and Wiegrebe, Wolfgang (1998) Anthranoid free radicals found in pseudomelanosis coli. PHARMAZIE, 53 (5). pp. 336-338. ISSN 0031-7144,
Full text not available from this repository.Abstract
Pseudomelanosis coli occurs after prolonged intake of anthranoids. After discontinuation of intake the pigmentation disappears apparently without noxious effects, including carcinogenicity and genotoxicity, We are presenting ESR spectra of pseudomelanosis coli specimen, compared to ESR spectra of pigmented skin scales taken from psoriatic patients heated topically with anthralin, and with ESR spectra of anthralin brown material formed in vitro. The ESR spectra show comparable g values within the accuracy of measurements. The examined specimens reveal remarkable stability: the intensity of the ESR signal remained practically constant over the period of four years. The chemical and physicochemical properties of the brown pigments formed from anthranoids explain the observed bio-inertness of these materials including that of melanosis coli pigment derived from anthranoids.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HAIRLESS MICE; SKIN; |
| Subjects: | 600 Technology > 615 Pharmacy |
| Divisions: | Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 20 Jun 2023 10:15 |
| Last Modified: | 20 Jun 2023 10:15 |
| URI: | https://pred.uni-regensburg.de/id/eprint/49870 |
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